PENICILLIN V BENZATHINE: 121 Adverse Event Reports & Safety Profile
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121
Total FAERS Reports
12 (9.9%)
Deaths Reported
59
Hospitalizations
121
As Primary/Secondary Suspect
11
Life-Threatening
15
Disabilities
First Report: 2000 · Latest Report: 20250204
What Are the Most Common PENICILLIN V BENZATHINE Side Effects?
#1 Most Reported
Drug hypersensitivity
12 reports (9.9%)
#2 Most Reported
Condition aggravated
10 reports (8.3%)
#3 Most Reported
Urticaria
9 reports (7.4%)
All PENICILLIN V BENZATHINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Drug hypersensitivity | 12 | 9.9% | 1 | 1 |
| Condition aggravated | 10 | 8.3% | 5 | 5 |
| Eosinophilia | 9 | 7.4% | 5 | 8 |
| Off label use | 9 | 7.4% | 5 | 7 |
| Rash | 9 | 7.4% | 0 | 5 |
| Urticaria | 9 | 7.4% | 0 | 2 |
| Headache | 8 | 6.6% | 0 | 0 |
| Rash maculo-papular | 8 | 6.6% | 5 | 8 |
| Acute generalised exanthematous pustulosis | 7 | 5.8% | 0 | 7 |
| Toxic epidermal necrolysis | 7 | 5.8% | 3 | 4 |
| Anxiety | 6 | 5.0% | 0 | 0 |
| Disturbance in attention | 6 | 5.0% | 0 | 0 |
| Drug reaction with eosinophilia and systemic symptoms | 6 | 5.0% | 5 | 6 |
| Hypoacusis | 6 | 5.0% | 0 | 0 |
| Memory impairment | 6 | 5.0% | 0 | 0 |
| Pyrexia | 6 | 5.0% | 0 | 5 |
| Restlessness | 6 | 5.0% | 0 | 0 |
| Tinnitus | 6 | 5.0% | 0 | 0 |
| Adenocarcinoma pancreas | 5 | 4.1% | 5 | 5 |
| Ear congestion | 5 | 4.1% | 0 | 0 |
Who Reports PENICILLIN V BENZATHINE Side Effects? Age & Gender Data
Gender: 52.7% female, 47.3% male. Average age: 43.4 years. Most reports from: FR. View detailed demographics →
Is PENICILLIN V BENZATHINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 4 | 0 | 0 |
| 2002 | 1 | 0 | 0 |
| 2007 | 1 | 0 | 0 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 6 | 0 | 5 |
| 2015 | 12 | 7 | 7 |
| 2016 | 6 | 2 | 3 |
| 2017 | 11 | 0 | 9 |
| 2018 | 15 | 1 | 8 |
| 2019 | 10 | 0 | 7 |
| 2020 | 11 | 0 | 7 |
| 2021 | 5 | 1 | 2 |
| 2022 | 11 | 0 | 1 |
| 2023 | 6 | 0 | 4 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
What Is PENICILLIN V BENZATHINE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 32 |
| Prophylaxis | 22 |
| Antibiotic prophylaxis | 13 |
| Infection prophylaxis | 5 |
| Streptococcal infection | 5 |
PENICILLIN V BENZATHINE vs Alternatives: Which Is Safer?
PENICILLIN V BENZATHINE vs PENTAMIDINE
PENICILLIN V BENZATHINE vs PENTAMIDINE ISETHIONATE
PENICILLIN V BENZATHINE vs PENTAZOCINE
PENICILLIN V BENZATHINE vs PENTOBARBITAL
PENICILLIN V BENZATHINE vs PENTOSAN POLYSULFATE
PENICILLIN V BENZATHINE vs PENTOSTATIN
PENICILLIN V BENZATHINE vs PENTOXIFYLLINE
PENICILLIN V BENZATHINE vs PERAMIVIR
PENICILLIN V BENZATHINE vs PERAMPANEL
PENICILLIN V BENZATHINE vs PERAZINE
Official FDA Label for PENICILLIN V BENZATHINE
Official prescribing information from the FDA-approved drug label.