PENTOBARBITAL for Generalised tonic-clonic seizure: Side Effects & Safety Data
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There are 33 adverse event reports in the FDA FAERS database where PENTOBARBITAL was used for Generalised tonic-clonic seizure.
Most Reported Side Effects for PENTOBARBITAL
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 117 | 26.3% | 22 | 87 |
| Off label use | 101 | 22.7% | 31 | 82 |
| Toxicity to various agents | 76 | 17.1% | 61 | 26 |
| Drug ineffective for unapproved indication | 75 | 16.9% | 27 | 68 |
| Status epilepticus | 59 | 13.3% | 33 | 40 |
| Completed suicide | 49 | 11.0% | 49 | 6 |
| Metabolic acidosis | 42 | 9.4% | 33 | 30 |
| Drug hypersensitivity | 41 | 9.2% | 21 | 31 |
| Propofol infusion syndrome | 36 | 8.1% | 33 | 28 |
| Shock | 35 | 7.9% | 33 | 27 |
| Arrhythmia | 33 | 7.4% | 33 | 26 |
| Gene mutation | 33 | 7.4% | 33 | 26 |
| Mitochondrial dna mutation | 33 | 7.4% | 33 | 26 |
| Multiple-drug resistance | 33 | 7.4% | 21 | 21 |
| Blood creatine phosphokinase increased | 32 | 7.2% | 32 | 25 |
Other Indications for PENTOBARBITAL
Status epilepticus (145)
Product used for unknown indication (82)
Febrile infection-related epilepsy syndrome (47)
Seizure (25)
Epilepsy (17)
Partial seizures (12)
Sedative therapy (11)
Intracranial pressure increased (10)
Sedation (10)
New onset refractory status epilepticus (9)
Other Drugs Used for Generalised tonic-clonic seizure
LEVETIRACETAM (2,753)
PHENYTOIN (755)
LAMOTRIGINE (717)
VALPROIC ACID (575)
LACOSAMIDE (495)
TOPIRAMATE (361)
CARBAMAZEPINE (355)
CLOBAZAM (307)
VALPROATE (254)
PHENOBARBITAL (213)