PERJETA: 228 Adverse Event Reports & Safety Profile
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228
Total FAERS Reports
44 (19.3%)
Deaths Reported
80
Hospitalizations
228
As Primary/Secondary Suspect
21
Life-Threatening
2
Disabilities
First Report: 2008 · Latest Report: 20140605
What Are the Most Common PERJETA Side Effects?
#1 Most Reported
Diarrhoea
30 reports (13.2%)
#2 Most Reported
Rash
24 reports (10.5%)
#3 Most Reported
Dyspnoea
24 reports (10.5%)
All PERJETA Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 30 | 13.2% | 2 | 14 |
| Dyspnoea | 24 | 10.5% | 0 | 7 |
| Rash | 24 | 10.5% | 0 | 8 |
| Disease progression | 22 | 9.7% | 7 | 2 |
| Nausea | 18 | 7.9% | 0 | 8 |
| Interstitial lung disease | 17 | 7.5% | 4 | 8 |
| Febrile neutropenia | 16 | 7.0% | 2 | 6 |
| Death | 15 | 6.6% | 15 | 1 |
| Pyrexia | 10 | 4.4% | 0 | 8 |
| Dehydration | 9 | 4.0% | 0 | 8 |
| Fatigue | 9 | 4.0% | 0 | 1 |
| Pruritus | 9 | 4.0% | 0 | 1 |
| Vomiting | 9 | 4.0% | 1 | 3 |
| Hypersensitivity | 8 | 3.5% | 0 | 2 |
| Cough | 7 | 3.1% | 0 | 3 |
| Hypotension | 7 | 3.1% | 0 | 3 |
| Mucosal inflammation | 7 | 3.1% | 2 | 6 |
| Anaemia | 6 | 2.6% | 3 | 2 |
| Erythema | 6 | 2.6% | 0 | 2 |
| Hypoaesthesia | 6 | 2.6% | 0 | 1 |
Who Reports PERJETA Side Effects? Age & Gender Data
Average age: 57.8 years. Most reports from: US. View detailed demographics →
Is PERJETA Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2008 | 1 | 0 | 0 |
| 2009 | 2 | 0 | 0 |
| 2012 | 3 | 0 | 3 |
| 2013 | 42 | 12 | 18 |
| 2014 | 60 | 9 | 29 |
What Is PERJETA Used For?
| Indication | Reports |
|---|---|
| Breast cancer metastatic | 90 |
| Breast cancer | 68 |
| Product used for unknown indication | 39 |
| Her-2 positive breast cancer | 20 |
| Breast cancer recurrent | 6 |
PERJETA vs Alternatives: Which Is Safer?
PERJETA vs PERMETHRIN
PERJETA vs PEROSPIRONE
PERJETA vs PERPHENAZINE
PERJETA vs PERTUZUMAB
PERJETA vs PERTUZUMAB\TRASTUZUMAB
PERJETA vs PETROLATUM
PERJETA vs PEVONEDISTAT
PERJETA vs PEXIDARTINIB
PERJETA vs PHENACETIN
PERJETA vs PHENAZOPYRIDINE
Official FDA Label for PERJETA
Official prescribing information from the FDA-approved drug label.