PERTUZUMAB\TRASTUZUMAB: 177 Adverse Event Reports & Safety Profile
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177
Total FAERS Reports
14 (7.9%)
Deaths Reported
84
Hospitalizations
177
As Primary/Secondary Suspect
16
Life-Threatening
5
Disabilities
First Report: 20150101 · Latest Report: 20250918
What Are the Most Common PERTUZUMAB\TRASTUZUMAB Side Effects?
#1 Most Reported
Diarrhoea
24 reports (13.6%)
#2 Most Reported
Myelosuppression
15 reports (8.5%)
#3 Most Reported
Off label use
10 reports (5.6%)
All PERTUZUMAB\TRASTUZUMAB Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 24 | 13.6% | 1 | 16 |
| Myelosuppression | 15 | 8.5% | 0 | 5 |
| Off label use | 10 | 5.7% | 1 | 3 |
| Febrile neutropenia | 8 | 4.5% | 1 | 6 |
| Pneumonia | 8 | 4.5% | 1 | 7 |
| Pyrexia | 8 | 4.5% | 0 | 3 |
| Anaemia | 7 | 4.0% | 0 | 3 |
| Death | 7 | 4.0% | 7 | 1 |
| Acute kidney injury | 6 | 3.4% | 0 | 6 |
| Chills | 6 | 3.4% | 0 | 0 |
| Dehydration | 6 | 3.4% | 0 | 4 |
| Fatigue | 6 | 3.4% | 1 | 0 |
| Hypokalaemia | 6 | 3.4% | 0 | 5 |
| Neuropathy peripheral | 6 | 3.4% | 1 | 4 |
| Disease progression | 5 | 2.8% | 1 | 0 |
| Pneumonitis | 5 | 2.8% | 2 | 2 |
| Pneumothorax | 5 | 2.8% | 0 | 5 |
| Stomatitis | 5 | 2.8% | 0 | 2 |
| Urinary tract infection | 5 | 2.8% | 2 | 5 |
Who Reports PERTUZUMAB\TRASTUZUMAB Side Effects? Age & Gender Data
Gender: 87.9% female, 12.1% male. Average age: 58.1 years. Most reports from: CN. View detailed demographics →
Is PERTUZUMAB\TRASTUZUMAB Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2015 | 1 | 1 | 0 |
| 2019 | 3 | 1 | 2 |
| 2020 | 3 | 1 | 2 |
| 2021 | 11 | 3 | 4 |
| 2022 | 29 | 0 | 23 |
| 2023 | 43 | 3 | 31 |
| 2024 | 18 | 2 | 9 |
| 2025 | 26 | 0 | 9 |
What Is PERTUZUMAB\TRASTUZUMAB Used For?
| Indication | Reports |
|---|---|
| Breast cancer | 65 |
| Her2 positive breast cancer | 38 |
| Breast cancer metastatic | 30 |
| Neoplasm malignant | 12 |
| Product used for unknown indication | 9 |
PERTUZUMAB\TRASTUZUMAB vs Alternatives: Which Is Safer?
PERTUZUMAB\TRASTUZUMAB vs PETROLATUM
PERTUZUMAB\TRASTUZUMAB vs PEVONEDISTAT
PERTUZUMAB\TRASTUZUMAB vs PEXIDARTINIB
PERTUZUMAB\TRASTUZUMAB vs PHENACETIN
PERTUZUMAB\TRASTUZUMAB vs PHENAZOPYRIDINE
PERTUZUMAB\TRASTUZUMAB vs PHENCYCLIDINE
PERTUZUMAB\TRASTUZUMAB vs PHENELZINE
PERTUZUMAB\TRASTUZUMAB vs PHENOBARBITAL
PERTUZUMAB\TRASTUZUMAB vs PHENOLPHTHALEIN
PERTUZUMAB\TRASTUZUMAB vs PHENOTHIAZINE
Official FDA Label for PERTUZUMAB\TRASTUZUMAB
Official prescribing information from the FDA-approved drug label.