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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

PHENIRAMINE: 67 Adverse Event Reports & Safety Profile

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67
Total FAERS Reports
19 (28.4%)
Deaths Reported
28
Hospitalizations
67
As Primary/Secondary Suspect
9
Life-Threatening
Poly Pharmaceuticals, Inc.
Manufacturer

Route: ORAL · Manufacturer: Poly Pharmaceuticals, Inc. · HUMAN OTC DRUG · FDA Label: Available

First Report: 2013 · Latest Report: 20240415

What Are the Most Common PHENIRAMINE Side Effects?

#1 Most Reported
Sepsis
8 reports (11.9%)
#2 Most Reported
Drug abuse
8 reports (11.9%)
#3 Most Reported
Urticaria
7 reports (10.4%)

All PHENIRAMINE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Drug abuse 8 11.9% 6 4
Sepsis 8 11.9% 6 5
Drug dependence 7 10.5% 4 6
Urticaria 7 10.5% 1 4
Dyspnoea 6 9.0% 3 2
Seizure 6 9.0% 0 0
Cardiac arrest 5 7.5% 4 2
Drug ineffective 5 7.5% 2 3
Hyperkalaemia 5 7.5% 5 4
Toxicity to various agents 5 7.5% 1 3
Ventricular fibrillation 5 7.5% 5 3

Who Reports PHENIRAMINE Side Effects? Age & Gender Data

Gender: 57.1% female, 42.9% male. Average age: 37.9 years. Most reports from: TR. View detailed demographics →

Is PHENIRAMINE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2013 5 3 2
2014 2 2 1
2015 2 0 2
2016 3 2 1
2017 1 0 0
2019 1 0 0
2023 1 0 0
2024 2 0 1

View full timeline →

What Is PHENIRAMINE Used For?

IndicationReports
Product used for unknown indication 24
Anaphylactic reaction 5

Official FDA Label for PHENIRAMINE

Official prescribing information from the FDA-approved drug label.

FDA Approved Uses (Indications)

USES Temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:  runny nose  sneezing  itching of the nose or throat  itchy, watery eyes  nasal congestion  reduces swelling of nasal passages

Dosage & Administration

DIRECTIONS Directions Adults and children 12 years of age and over 1 tablet every 4 hours, not to exceed 6 tablets in 24 hours Children 6 to under 12 years of age Children under 6 consult a doctor 1/2 tablet every 4 hours, not to exceed 3 tablets in 24 hours

Warnings

WARNINGS Do not exceed recommended dosage. Do not use this product  if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have  a breathing problem such as emphysema or chronic bronchitis  glaucoma  trouble urinating due to enlargement of the prostate gland  heart disease  high blood pressure  thyroid disease  diabetes Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product  excitability may occur, especially in children  may cause drowsiness  avoid alcoholic drinks  alcohol, sedatives, and tranquilizers may increase the drowsiness effect  use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if  nervousness, dizziness, or sleeplessness occur  symptoms do not improve within 7 days or are accompanied by fever If pregnant or breast-feeding, ask a health professional before use.

Active Ingredient

ACTIVE INGREDIENT Active Ingredient (in each tablet)

Purpose Pheniramine Maleate

17mg​ Antihistamine Phenylephrine HCl 10mg Nasal Decongestant

Inactive Ingredients

INACTIVE INGREDIENTS Inactive ingredients Magnesium Stearate, Microcrystalline Cellulose, Natural Yellow, Sodium Starch Glycolate