PIRARUBICIN: 1,348 Adverse Event Reports & Safety Profile
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1,348
Total FAERS Reports
143 (10.6%)
Deaths Reported
628
Hospitalizations
1,348
As Primary/Secondary Suspect
153
Life-Threatening
15
Disabilities
Active Ingredient: PIRARUBICIN HYDROCHLORIDE ·
First Report: 199708 · Latest Report: 20250911
What Are the Most Common PIRARUBICIN Side Effects?
#1 Most Reported
Myelosuppression
408 reports (30.3%)
#2 Most Reported
White blood cell count decreased
207 reports (15.4%)
#3 Most Reported
Neutrophil count decreased
145 reports (10.8%)
All PIRARUBICIN Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Myelosuppression | 408 | 30.3% | 5 | 260 |
| White blood cell count decreased | 207 | 15.4% | 9 | 114 |
| Neutrophil count decreased | 145 | 10.8% | 3 | 90 |
| Bone marrow failure | 127 | 9.4% | 14 | 55 |
| Nausea | 111 | 8.2% | 2 | 68 |
| Vomiting | 104 | 7.7% | 2 | 70 |
| Gastrointestinal disorder | 58 | 4.3% | 1 | 39 |
| Leukopenia | 55 | 4.1% | 0 | 21 |
| Pyrexia | 55 | 4.1% | 4 | 36 |
| Neutropenia | 54 | 4.0% | 13 | 18 |
| Febrile neutropenia | 53 | 3.9% | 13 | 16 |
| Decreased appetite | 50 | 3.7% | 7 | 20 |
| Platelet count decreased | 43 | 3.2% | 6 | 21 |
| Anaemia | 42 | 3.1% | 6 | 13 |
| Hepatic function abnormal | 41 | 3.0% | 3 | 11 |
| Agranulocytosis | 39 | 2.9% | 3 | 22 |
| Drug ineffective | 39 | 2.9% | 16 | 8 |
| Granulocytopenia | 37 | 2.7% | 0 | 25 |
| Off label use | 37 | 2.7% | 10 | 16 |
| Asthenia | 35 | 2.6% | 4 | 20 |
Who Reports PIRARUBICIN Side Effects? Age & Gender Data
Gender: 71.7% female, 28.3% male. Average age: 50.4 years. Most reports from: CN. View detailed demographics →
Is PIRARUBICIN Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 0 |
| 2008 | 2 | 2 | 2 |
| 2009 | 1 | 1 | 0 |
| 2011 | 4 | 2 | 0 |
| 2012 | 5 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 9 | 2 | 4 |
| 2015 | 18 | 5 | 10 |
| 2016 | 14 | 2 | 2 |
| 2017 | 11 | 1 | 4 |
| 2018 | 20 | 4 | 11 |
| 2019 | 70 | 0 | 47 |
| 2020 | 87 | 0 | 49 |
| 2021 | 121 | 0 | 77 |
| 2022 | 163 | 3 | 109 |
| 2023 | 137 | 1 | 88 |
| 2024 | 128 | 0 | 74 |
| 2025 | 67 | 0 | 39 |
What Is PIRARUBICIN Used For?
| Indication | Reports |
|---|---|
| Breast cancer female | 271 |
| Diffuse large b-cell lymphoma | 175 |
| Chemotherapy | 135 |
| Breast cancer | 82 |
| Lymphoma | 68 |
| Invasive ductal breast carcinoma | 56 |
| Acute lymphocytic leukaemia | 51 |
| Non-hodgkin's lymphoma | 40 |
| Neoplasm | 38 |
| B-cell lymphoma | 36 |
PIRARUBICIN vs Alternatives: Which Is Safer?
PIRARUBICIN vs PIRFENIDONE
PIRARUBICIN vs PIRIBEDIL
PIRARUBICIN vs PIRITRAMIDE
PIRARUBICIN vs PIROXICAM
PIRARUBICIN vs PIRTOBRUTINIB
PIRARUBICIN vs PIT VIPER IMMUNE GLOBULIN ANTIVENIN
PIRARUBICIN vs PITAVASTATIN
PIRARUBICIN vs PITOLISANT
PIRARUBICIN vs PIXANTRONE
PIRARUBICIN vs PIZOTYLINE
Official FDA Label for PIRARUBICIN
Official prescribing information from the FDA-approved drug label.