PIRFENIDONE for Pulmonary hypertension: Side Effects & Safety Data
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There are 92 adverse event reports in the FDA FAERS database where PIRFENIDONE was used for Pulmonary hypertension.
Most Reported Side Effects for PIRFENIDONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 7,221 | 19.0% | 7,159 | 291 |
| Nausea | 4,944 | 13.0% | 220 | 690 |
| Fatigue | 3,597 | 9.5% | 198 | 590 |
| Decreased appetite | 3,126 | 8.2% | 230 | 564 |
| Diarrhoea | 3,026 | 8.0% | 129 | 462 |
| Dyspnoea | 2,526 | 6.7% | 351 | 1,099 |
| Weight decreased | 2,113 | 5.6% | 203 | 424 |
| Dizziness | 2,027 | 5.3% | 96 | 359 |
| Rash | 1,982 | 5.2% | 70 | 185 |
| Cough | 1,692 | 4.5% | 139 | 428 |
| Vomiting | 1,673 | 4.4% | 66 | 303 |
| Pneumonia | 1,646 | 4.3% | 304 | 1,194 |
| Abdominal discomfort | 1,625 | 4.3% | 63 | 217 |
| Abdominal pain upper | 1,460 | 3.9% | 47 | 195 |
| Off label use | 1,362 | 3.6% | 175 | 187 |
Other Indications for PIRFENIDONE
Idiopathic pulmonary fibrosis (27,590)
Product used for unknown indication (4,961)
Pulmonary fibrosis (3,063)
Interstitial lung disease (1,657)
Pulmonary arterial hypertension (210)
Chronic obstructive pulmonary disease (115)
Pneumonia (114)
Idiopathic interstitial pneumonia (94)
Hypoxia (71)
Lung disorder (67)
Other Drugs Used for Pulmonary hypertension
AMBRISENTAN (18,885)
TREPROSTINIL (10,034)
MACITENTAN (5,228)
RIOCIGUAT (3,837)
SILDENAFIL (3,761)
SELEXIPAG (2,500)
EPOPROSTENOL (2,486)
TADALAFIL (2,430)
BOSENTAN (2,337)
ILOPROST (1,123)