PLATINUM: 328 Adverse Event Reports & Safety Profile
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Route: ORAL · Manufacturer: Boiron · HUMAN OTC DRUG · FDA Label: Available
First Report: 20130819 · Latest Report: 20240101
What Are the Most Common PLATINUM Side Effects?
All PLATINUM Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Disease progression | 43 | 13.1% | 5 | 9 |
| Off label use | 29 | 8.8% | 3 | 13 |
| Fatigue | 27 | 8.2% | 6 | 9 |
| Metabolic disorder | 24 | 7.3% | 0 | 0 |
| Thrombocytopenia | 24 | 7.3% | 1 | 4 |
| Pneumonitis | 23 | 7.0% | 4 | 6 |
| Anaemia | 22 | 6.7% | 2 | 4 |
| Malignant neoplasm progression | 22 | 6.7% | 7 | 6 |
| Neutropenia | 22 | 6.7% | 1 | 1 |
| Blood lactate dehydrogenase increased | 20 | 6.1% | 0 | 0 |
| Hepatitis b core antibody positive | 15 | 4.6% | 0 | 0 |
| Diarrhoea | 14 | 4.3% | 4 | 4 |
| Nausea | 14 | 4.3% | 1 | 1 |
| Vomiting | 14 | 4.3% | 4 | 5 |
| Acute kidney injury | 13 | 4.0% | 1 | 4 |
| Febrile neutropenia | 13 | 4.0% | 2 | 7 |
| Hepatotoxicity | 13 | 4.0% | 4 | 4 |
| Dyspnoea | 12 | 3.7% | 2 | 6 |
| Mucosal inflammation | 12 | 3.7% | 0 | 3 |
| Cough | 10 | 3.1% | 5 | 5 |
Who Reports PLATINUM Side Effects? Age & Gender Data
Gender: 40.1% female, 59.9% male. Average age: 56.5 years. Most reports from: US. View detailed demographics →
Is PLATINUM Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2013 | 2 | 0 | 0 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 7 | 2 | 3 |
| 2018 | 6 | 1 | 3 |
| 2019 | 15 | 4 | 5 |
| 2020 | 18 | 5 | 8 |
| 2021 | 12 | 0 | 7 |
| 2022 | 7 | 0 | 6 |
| 2023 | 2 | 1 | 1 |
| 2024 | 1 | 0 | 0 |
What Is PLATINUM Used For?
PLATINUM vs Alternatives: Which Is Safer?
Official FDA Label for PLATINUM
Official prescribing information from the FDA-approved drug label.
FDA Approved Uses (Indications)
Constipation while traveling*
Dosage & Administration
Adults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
Active Ingredient
Platinum metallicum 12C (**contains 0.443 mg of the active ingredient per pellet)
Inactive Ingredients
lactose, sucrose