PLERIXAFOR for Haematopoietic stem cell mobilisation: Side Effects & Safety Data
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There are 151 adverse event reports in the FDA FAERS database where PLERIXAFOR was used for Haematopoietic stem cell mobilisation.
Most Reported Side Effects for PLERIXAFOR
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 69 | 15.4% | 13 | 18 |
| Mucosal inflammation | 47 | 10.5% | 6 | 3 |
| Nausea | 29 | 6.5% | 2 | 11 |
| Off label use | 29 | 6.5% | 4 | 4 |
| Dyspnoea | 28 | 6.3% | 1 | 19 |
| Pyrexia | 27 | 6.0% | 6 | 16 |
| Diarrhoea | 24 | 5.4% | 7 | 6 |
| Thrombocytopenia | 23 | 5.2% | 2 | 6 |
| Acute kidney injury | 21 | 4.7% | 2 | 18 |
| Acute respiratory distress syndrome | 20 | 4.5% | 3 | 17 |
| Escherichia infection | 18 | 4.0% | 6 | 11 |
| Alanine aminotransferase increased | 17 | 3.8% | 1 | 16 |
| Colitis | 17 | 3.8% | 0 | 16 |
| Herpes simplex | 17 | 3.8% | 3 | 0 |
| Stomatitis | 17 | 3.8% | 1 | 2 |
Other Indications for PLERIXAFOR
Plasma cell myeloma (30)
Bone marrow conditioning regimen (21)
Diffuse large b-cell lymphoma (17)
Product used for unknown indication (17)
Transplant (16)
Acute myeloid leukaemia (13)
Stem cell transplant (11)
Non-hodgkin's lymphoma (9)
Peripheral blood stem cell apheresis (9)
Combined immunodeficiency (8)
Other Drugs Used for Haematopoietic stem cell mobilisation
FILGRASTIM (988)
CYCLOPHOSPHAMIDE (254)
PEGFILGRASTIM (109)
ETOPOSIDE (56)
GRANULOCYTE COLONY-STIMULATING FACTOR NOS (51)
CYTARABINE (23)
LENOGRASTIM (22)
BUSULFAN (18)
DEXAMETHASONE (18)
FLUDARABINE (16)