Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

POLYETHYLENE GLYCOL 4000: 984 Adverse Event Reports & Safety Profile

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now
984
Total FAERS Reports
246 (25.0%)
Deaths Reported
521
Hospitalizations
984
As Primary/Secondary Suspect
191
Life-Threatening
155
Disabilities

First Report: 2006 · Latest Report: 20250906

What Are the Most Common POLYETHYLENE GLYCOL 4000 Side Effects?

#1 Most Reported
Off label use
181 reports (18.4%)
#2 Most Reported
Constipation
178 reports (18.1%)
#3 Most Reported
Nausea
177 reports (18.0%)

All POLYETHYLENE GLYCOL 4000 Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Off label use 181 18.4% 108 150
Constipation 178 18.1% 120 150
Nausea 177 18.0% 108 147
Abdominal pain 166 16.9% 112 138
Hyponatraemia 154 15.7% 118 124
Vomiting 153 15.6% 134 113
Anaemia 148 15.0% 87 145
Drug ineffective 146 14.8% 36 99
Abdominal distension 125 12.7% 124 101
Ascites 125 12.7% 125 89
Ventricular fibrillation 124 12.6% 124 97
Appendicitis 116 11.8% 116 89
Appendicolith 115 11.7% 115 88
General physical health deterioration 114 11.6% 112 85
Multiple organ dysfunction syndrome 113 11.5% 113 85
Somnolence 112 11.4% 99 98
Cardiogenic shock 111 11.3% 111 84
Sepsis 111 11.3% 111 83
Stress 110 11.2% 110 83
Macular degeneration 106 10.8% 0 64

Who Reports POLYETHYLENE GLYCOL 4000 Side Effects? Age & Gender Data

Gender: 41.6% female, 58.4% male. Average age: 70.4 years. Most reports from: CA. View detailed demographics →

Is POLYETHYLENE GLYCOL 4000 Getting Safer? Reports by Year

YearReportsDeathsHosp.
2006 1 0 0
2007 3 0 3
2008 1 0 0
2010 2 0 0
2011 1 0 0
2012 7 0 5
2013 15 4 5
2014 10 0 9
2015 22 4 11
2016 39 0 27
2017 124 1 42
2018 105 10 53
2019 81 8 42
2020 110 55 92
2021 41 15 14
2022 31 10 5
2023 24 1 2
2024 61 14 30
2025 28 10 18

View full timeline →

What Is POLYETHYLENE GLYCOL 4000 Used For?

IndicationReports
Constipation 490
Product used for unknown indication 371
Iron deficiency 20
Normochromic normocytic anaemia 14
Diabetes mellitus 12
Dyspnoea 12
Thrombosis 12
Chemotherapy side effect prophylaxis 10
Wrong patient received product 10
Type 2 diabetes mellitus 8

POLYETHYLENE GLYCOL 4000 vs Alternatives: Which Is Safer?

POLYETHYLENE GLYCOL 4000 vs POLYETHYLENE GLYCOL 400\PROPYLENE GLYCOL POLYETHYLENE GLYCOL 4000 vs POLYETHYLENE GLYCOL\POTASSIUM\SODIUM BICARBONATE POLYETHYLENE GLYCOL 4000 vs POLYETHYLENE GLYCOL\POTASSIUM\SODIUM BICARBONATE\SODIUM POLYETHYLENE GLYCOL 4000 vs POLYETHYLENE GLYCOLS POLYETHYLENE GLYCOL 4000 vs POLYMYXIN B POLYETHYLENE GLYCOL 4000 vs POLYMYXIN B\TRIMETHOPRIM POLYETHYLENE GLYCOL 4000 vs POLYVINYL ALCOHOL\POVIDONE POLYETHYLENE GLYCOL 4000 vs POMALIDOMIDE POLYETHYLENE GLYCOL 4000 vs POMALYST POLYETHYLENE GLYCOL 4000 vs PONATINIB

Official FDA Label for POLYETHYLENE GLYCOL 4000

Official prescribing information from the FDA-approved drug label.