PONATINIB for B precursor type acute leukaemia: Side Effects & Safety Data
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There are 33 adverse event reports in the FDA FAERS database where PONATINIB was used for B precursor type acute leukaemia.
Most Reported Side Effects for PONATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 1,735 | 17.3% | 1,735 | 548 |
| Off label use | 1,071 | 10.7% | 287 | 488 |
| Product dose omission issue | 817 | 8.2% | 159 | 481 |
| Fatigue | 687 | 6.9% | 131 | 385 |
| Rash | 639 | 6.4% | 122 | 299 |
| Headache | 553 | 5.5% | 78 | 293 |
| Pyrexia | 542 | 5.4% | 129 | 406 |
| Nausea | 466 | 4.7% | 62 | 265 |
| Hospitalisation | 459 | 4.6% | 70 | 458 |
| Constipation | 435 | 4.4% | 74 | 253 |
| Drug ineffective | 406 | 4.1% | 82 | 157 |
| Arthralgia | 386 | 3.9% | 49 | 206 |
| Dry skin | 381 | 3.8% | 69 | 205 |
| Platelet count decreased | 379 | 3.8% | 108 | 224 |
| Hypertension | 370 | 3.7% | 52 | 177 |
Other Indications for PONATINIB
Chronic myeloid leukaemia (4,723)
Acute lymphocytic leukaemia (2,408)
Product used for unknown indication (855)
Philadelphia positive acute lymphocytic leukaemia (487)
Acute myeloid leukaemia (284)
Acute lymphocytic leukaemia recurrent (195)
Acute lymphocytic leukaemia (in remission) (116)
Chronic myeloid leukaemia transformation (114)
Myeloid leukaemia (110)
Chronic myeloid leukaemia (in remission) (90)
Other Drugs Used for B precursor type acute leukaemia
BLINATUMOMAB (1,791)
METHOTREXATE (1,067)
VINCRISTINE (977)
DEXAMETHASONE (662)
CYTARABINE (644)
CYCLOPHOSPHAMIDE (598)
PEGASPARGASE (531)
MERCAPTOPURINE (484)
DOXORUBICIN (331)
DAUNORUBICIN (274)