Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

PROPOXYPHENE: 4,444 Adverse Event Reports & Safety Profile

Grow Your Own Natural Pharmacy at Home

Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.

Get the Kit
4,444
Total FAERS Reports
402 (9.0%)
Deaths Reported
156
Hospitalizations
4,444
As Primary/Secondary Suspect
9
Life-Threatening
417
Disabilities
Approved Prior to Jan 1, 1982
FDA Approved
Discontinued
Status
Yes
Generic Available

Active Ingredient: PROPOXYPHENE HYDROCHLORIDE · FDA Application: 010997 ·

First Report: 19790101 · Latest Report: 20230814

What Are the Most Common PROPOXYPHENE Side Effects?

#1 Most Reported
Dependence
3,206 reports (72.1%)
#2 Most Reported
Overdose
585 reports (13.2%)
#3 Most Reported
Back pain
424 reports (9.5%)

All PROPOXYPHENE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Dependence 3,206 72.1% 123 7
Overdose 585 13.2% 130 25
Back pain 424 9.5% 2 0
Cardiovascular disorder 399 9.0% 40 1
Movement disorder 399 9.0% 39 2
Nervous system disorder 399 9.0% 40 1
Drug hypersensitivity 337 7.6% 0 5
Pain 244 5.5% 3 64
Back injury 239 5.4% 0 2
Death 214 4.8% 212 10
Toxicity to various agents 142 3.2% 127 31
Arthralgia 122 2.8% 3 0
Nausea 103 2.3% 2 66
Headache 95 2.1% 2 64
Road traffic accident 94 2.1% 4 6
Drug ineffective 81 1.8% 4 69
Off label use 78 1.8% 11 72
Spinal operation 75 1.7% 0 0
Constipation 73 1.6% 2 61
Malaise 70 1.6% 0 65

Who Reports PROPOXYPHENE Side Effects? Age & Gender Data

Gender: 53.2% female, 46.8% male. Average age: 58.2 years. Most reports from: US. View detailed demographics →

Is PROPOXYPHENE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2002 2 1 0
2003 2 0 1
2004 2 2 1
2005 3 2 1
2006 5 2 3
2007 5 2 1
2008 4 1 1
2009 2 2 0
2010 6 4 5
2011 2 0 0
2012 15 13 0
2013 4 1 0
2014 2 0 1
2015 3 3 0
2016 3 1 1
2017 9 1 1
2018 7 0 5
2019 6 5 0
2021 1 0 0
2022 2 0 1
2023 3 1 0

View full timeline →

What Is PROPOXYPHENE Used For?

IndicationReports
Pain 421
Product used for unknown indication 409
Dysmenorrhoea 9
Suicide attempt 8
Nasal septal operation 5
Sunct syndrome 5

PROPOXYPHENE vs Alternatives: Which Is Safer?

PROPOXYPHENE vs PROPOXYPHENE/ACETAMINOPHEN PROPOXYPHENE vs PROPRANOLOL PROPOXYPHENE vs PROPRANOLOL\PROPRANOLOL PROPOXYPHENE vs PROPYLENE GLYCOL PROPOXYPHENE vs PROPYLTHIOURACIL PROPOXYPHENE vs PROTAMINE PROPOXYPHENE vs PROTHIPENDYL PROPOXYPHENE vs PROTIONAMIDE PROPOXYPHENE vs PROTONIX PROPOXYPHENE vs PROTOPIC

Official FDA Label for PROPOXYPHENE

Official prescribing information from the FDA-approved drug label.