PROTAMINE for Heparin neutralisation therapy: Side Effects & Safety Data

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There are 61 adverse event reports in the FDA FAERS database where PROTAMINE was used for Heparin neutralisation therapy.

Most Reported Side Effects for PROTAMINE

Side Effect	Reports	%	Deaths	Hosp.
Hypotension	133	22.4%	15	26
Anaphylactic reaction	64	10.8%	8	19
Drug ineffective	59	9.9%	13	14
Post procedural haemorrhage	49	8.2%	5	15
Cardiac arrest	36	6.1%	14	9
Therapeutic product effect decreased	31	5.2%	0	0
Haemorrhage	29	4.9%	12	12
Blood pressure decreased	27	4.5%	4	3
Bradycardia	27	4.5%	6	8
Circulatory collapse	26	4.4%	11	6
Vasoplegia syndrome	18	3.0%	4	12
Dyspnoea	17	2.9%	1	3
Pulmonary hypertension	17	2.9%	5	6
Hypersensitivity	16	2.7%	6	3
Drug interaction	15	2.5%	1	11