PYROTINIB for Chemotherapy: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where PYROTINIB was used for Chemotherapy.
Most Reported Side Effects for PYROTINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Myelosuppression | 62 | 25.3% | 2 | 35 |
| Diarrhoea | 57 | 23.3% | 6 | 10 |
| Vomiting | 39 | 15.9% | 3 | 7 |
| Nausea | 35 | 14.3% | 4 | 4 |
| Alanine aminotransferase increased | 32 | 13.1% | 3 | 14 |
| Anaemia | 28 | 11.4% | 3 | 1 |
| Palmar-plantar erythrodysaesthesia syndrome | 28 | 11.4% | 2 | 1 |
| Aspartate aminotransferase increased | 26 | 10.6% | 3 | 8 |
| Hypokalaemia | 25 | 10.2% | 3 | 9 |
| White blood cell count decreased | 25 | 10.2% | 4 | 10 |
| Fatigue | 22 | 9.0% | 3 | 0 |
| Disease progression | 21 | 8.6% | 0 | 4 |
| Thrombocytopenia | 21 | 8.6% | 0 | 1 |
| Decreased appetite | 20 | 8.2% | 6 | 1 |
| Neutropenia | 20 | 8.2% | 0 | 0 |
Other Indications for PYROTINIB
Breast cancer (70)
Breast cancer metastatic (52)
Her2 positive breast cancer (44)
Invasive ductal breast carcinoma (19)
Invasive breast carcinoma (8)
Metastases to central nervous system (7)
Other Drugs Used for Chemotherapy
CYCLOPHOSPHAMIDE (3,372)
DOCETAXEL (2,134)
CARBOPLATIN (1,902)
DOXORUBICIN (1,756)
VINCRISTINE (1,743)
PACLITAXEL (1,425)
OXALIPLATIN (1,423)
METHOTREXATE (1,380)
CYTARABINE (1,355)
ETOPOSIDE (1,246)