REGORAFENIB for Colon cancer: Side Effects & Safety Data
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There are 1,699 adverse event reports in the FDA FAERS database where REGORAFENIB was used for Colon cancer.
Most Reported Side Effects for REGORAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,906 | 20.2% | 244 | 702 |
| Fatigue | 1,530 | 16.2% | 168 | 556 |
| Palmar-plantar erythrodysaesthesia syndrome | 1,230 | 13.0% | 201 | 297 |
| Diarrhoea | 1,221 | 12.9% | 174 | 418 |
| Decreased appetite | 941 | 10.0% | 146 | 408 |
| Asthenia | 825 | 8.7% | 159 | 373 |
| Death | 813 | 8.6% | 810 | 166 |
| Dysphonia | 702 | 7.4% | 57 | 232 |
| Nausea | 688 | 7.3% | 86 | 312 |
| Pain in extremity | 686 | 7.3% | 31 | 197 |
| Pyrexia | 626 | 6.6% | 85 | 422 |
| Hypertension | 606 | 6.4% | 77 | 201 |
| Weight decreased | 574 | 6.1% | 82 | 217 |
| Vomiting | 477 | 5.1% | 64 | 267 |
| Pain | 473 | 5.0% | 53 | 169 |
Other Indications for REGORAFENIB
Colorectal cancer (1,313)
Colorectal cancer metastatic (1,234)
Hepatocellular carcinoma (1,050)
Rectal cancer (505)
Gastrointestinal stromal tumour (473)
Product used for unknown indication (253)
Hepatic cancer (252)
Metastases to liver (252)
Colon cancer metastatic (205)
Metastases to lung (157)
Other Drugs Used for Colon cancer
CAPECITABINE (6,498)
OXALIPLATIN (5,829)
TIPIRACIL\TRIFLURIDINE (4,053)
BEVACIZUMAB (4,015)
FLUOROURACIL (3,771)
IRINOTECAN (2,105)
PANITUMUMAB (1,726)
CETUXIMAB (1,522)
LEUCOVORIN (1,364)
ENCORAFENIB (1,294)