Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

RIBOFLAVIN: 849 Adverse Event Reports & Safety Profile

Grow Your Own Natural Pharmacy at Home

Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.

Get the Kit
849
Total FAERS Reports
407 (47.9%)
Deaths Reported
570
Hospitalizations
849
As Primary/Secondary Suspect
382
Life-Threatening
388
Disabilities

First Report: 1999 · Latest Report: 20250314

What Are the Most Common RIBOFLAVIN Side Effects?

#1 Most Reported
Off label use
410 reports (48.3%)
#2 Most Reported
Drug ineffective
372 reports (43.8%)
#3 Most Reported
Nausea
271 reports (31.9%)

All RIBOFLAVIN Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Off label use 410 48.3% 281 334
Drug ineffective 372 43.8% 227 313
Nausea 271 31.9% 231 250
Drug hypersensitivity 270 31.8% 225 224
Product use in unapproved indication 265 31.2% 199 210
Pain 264 31.1% 202 226
Infusion related reaction 225 26.5% 199 223
Swelling 223 26.3% 223 221
Sleep disorder 214 25.2% 214 212
Pericarditis 210 24.7% 210 209
Dyspnoea 208 24.5% 208 206
Synovitis 204 24.0% 204 203
Rash 200 23.6% 197 199
Drug intolerance 194 22.9% 153 152
Systemic lupus erythematosus 194 22.9% 194 193
Gastrooesophageal reflux disease 193 22.7% 115 162
Pemphigus 193 22.7% 193 192
Confusional state 191 22.5% 187 190
Hypertension 188 22.1% 141 186
Rheumatoid arthritis 188 22.1% 188 188

Who Reports RIBOFLAVIN Side Effects? Age & Gender Data

Gender: 78.5% female, 21.5% male. Average age: 50.7 years. Most reports from: CA. View detailed demographics →

Is RIBOFLAVIN Getting Safer? Reports by Year

YearReportsDeathsHosp.
2006 26 0 0
2010 1 0 0
2013 1 0 0
2014 1 0 0
2015 8 6 6
2016 1 0 0
2017 4 0 0
2018 2 0 2
2020 36 14 14
2021 2 1 2
2023 4 0 2
2024 2 0 1
2025 1 0 1

View full timeline →

What Is RIBOFLAVIN Used For?

IndicationReports
Product used for unknown indication 599
Complex regional pain syndrome 64
Migraine prophylaxis 64
Nutritional supplementation 21
Ill-defined disorder 17
Migraine 15
Mitochondrial encephalomyopathy 11
Supplementation therapy 11
Foetal exposure during pregnancy 8
Occipital neuralgia 5

RIBOFLAVIN vs Alternatives: Which Is Safer?

RIBOFLAVIN vs RIBOFLAVIN 5'-PHOSPHATE RIBOFLAVIN vs RIBOFLAVIN 5^-PHOSPHATE RIBOFLAVIN vs RIFABUTIN RIBOFLAVIN vs RIFAMPICIN RIBOFLAVIN vs RIFAMPIN RIBOFLAVIN vs RIFAMYCIN RIBOFLAVIN vs RIFAPENTINE RIBOFLAVIN vs RIFAXIMIN RIBOFLAVIN vs RILMENIDINE RIBOFLAVIN vs RILONACEPT

Official FDA Label for RIBOFLAVIN

Official prescribing information from the FDA-approved drug label.