RILMENIDINE: 899 Adverse Event Reports & Safety Profile
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899
Total FAERS Reports
103 (11.5%)
Deaths Reported
536
Hospitalizations
899
As Primary/Secondary Suspect
178
Life-Threatening
21
Disabilities
First Report: 20050101 · Latest Report: 20250410
What Are the Most Common RILMENIDINE Side Effects?
#1 Most Reported
Acute kidney injury
214 reports (23.8%)
#2 Most Reported
Lactic acidosis
121 reports (13.5%)
#3 Most Reported
Fall
120 reports (13.3%)
All RILMENIDINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Acute kidney injury | 214 | 23.8% | 12 | 139 |
| Lactic acidosis | 121 | 13.5% | 28 | 46 |
| Fall | 120 | 13.4% | 0 | 107 |
| Hyperkalaemia | 86 | 9.6% | 5 | 54 |
| Hypotension | 85 | 9.5% | 4 | 75 |
| Hypoglycaemia | 59 | 6.6% | 0 | 21 |
| Diarrhoea | 49 | 5.5% | 5 | 30 |
| Bradycardia | 45 | 5.0% | 0 | 14 |
| Rhabdomyolysis | 44 | 4.9% | 0 | 17 |
| Drug ineffective | 41 | 4.6% | 0 | 32 |
| Dyspnoea | 39 | 4.3% | 11 | 29 |
| Hyponatraemia | 37 | 4.1% | 0 | 26 |
| Oedema peripheral | 36 | 4.0% | 5 | 24 |
| Confusional state | 32 | 3.6% | 0 | 30 |
| Fatigue | 32 | 3.6% | 0 | 22 |
| Off label use | 31 | 3.5% | 15 | 6 |
| Somnolence | 31 | 3.5% | 4 | 26 |
| Tachycardia | 31 | 3.5% | 4 | 21 |
| Pemphigoid | 30 | 3.3% | 0 | 22 |
| Angioedema | 29 | 3.2% | 0 | 1 |
Who Reports RILMENIDINE Side Effects? Age & Gender Data
Gender: 65.3% female, 34.7% male. Average age: 73.4 years. Most reports from: FR. View detailed demographics →
Is RILMENIDINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2005 | 2 | 0 | 0 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 4 | 3 | 4 |
| 2012 | 10 | 0 | 2 |
| 2013 | 13 | 1 | 9 |
| 2014 | 31 | 1 | 28 |
| 2015 | 37 | 4 | 34 |
| 2016 | 59 | 6 | 44 |
| 2017 | 97 | 4 | 42 |
| 2018 | 116 | 1 | 54 |
| 2019 | 119 | 25 | 66 |
| 2020 | 76 | 11 | 47 |
| 2021 | 47 | 0 | 25 |
| 2022 | 58 | 7 | 42 |
| 2023 | 14 | 0 | 4 |
| 2024 | 53 | 24 | 17 |
| 2025 | 14 | 0 | 14 |
What Is RILMENIDINE Used For?
| Indication | Reports |
|---|---|
| Hypertension | 661 |
| Product used for unknown indication | 126 |
| Poisoning deliberate | 11 |
| Medication error | 10 |
| Drug administration error | 7 |
| Essential hypertension | 6 |
| Suicide attempt | 5 |
RILMENIDINE vs Alternatives: Which Is Safer?
RILMENIDINE vs RILONACEPT
RILMENIDINE vs RILPIVIRINE
RILMENIDINE vs RILUZOLE
RILMENIDINE vs RIMABOTULINUMTOXINB
RILMENIDINE vs RIMEGEPANT
RILMENIDINE vs RIOCIGUAT
RILMENIDINE vs RIPRETINIB
RILMENIDINE vs RISANKIZUMAB
RILMENIDINE vs RISANKIZUMAB-RZAA
RILMENIDINE vs RISDIPLAM
Official FDA Label for RILMENIDINE
Official prescribing information from the FDA-approved drug label.