ROMIPLOSTIM for Evans syndrome: Side Effects & Safety Data
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There are 39 adverse event reports in the FDA FAERS database where ROMIPLOSTIM was used for Evans syndrome.
Most Reported Side Effects for ROMIPLOSTIM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,027 | 13.7% | 110 | 184 |
| Platelet count decreased | 892 | 11.9% | 42 | 253 |
| Platelet count abnormal | 703 | 9.4% | 9 | 128 |
| Drug ineffective | 513 | 6.8% | 48 | 137 |
| Thrombocytopenia | 369 | 4.9% | 37 | 198 |
| Headache | 359 | 4.8% | 19 | 84 |
| Death | 356 | 4.7% | 356 | 87 |
| Product storage error | 344 | 4.6% | 0 | 3 |
| Fatigue | 251 | 3.3% | 16 | 53 |
| Circumstance or information capable of leading to medication error | 238 | 3.2% | 0 | 1 |
| Thrombocytosis | 234 | 3.1% | 10 | 103 |
| Therapy non-responder | 224 | 3.0% | 24 | 50 |
| Nausea | 192 | 2.6% | 16 | 40 |
| Platelet count increased | 192 | 2.6% | 11 | 65 |
| Haemorrhage | 187 | 2.5% | 36 | 78 |
Other Indications for ROMIPLOSTIM
Immune thrombocytopenic purpura (2,600)
Product used for unknown indication (2,223)
Immune thrombocytopenia (1,358)
Thrombocytopenia (586)
Aplastic anaemia (231)
Platelet count decreased (82)
Thrombocytopenic purpura (53)
Myelodysplastic syndrome (51)
Off label use (48)
Exposure during pregnancy (29)
Other Drugs Used for Evans syndrome
RITUXIMAB (167)
PREDNISONE (60)
MYCOPHENOLATE MOFETIL (44)
HUMAN IMMUNOGLOBULIN G (40)
METHYLPREDNISOLONE (33)
PREDNISOLONE (30)
CYCLOSPORINE (27)
ELTROMBOPAG (26)
DEXAMETHASONE (24)
SIROLIMUS (23)