RUXOLITINIB for Essential thrombocythaemia: Side Effects & Safety Data
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There are 1,788 adverse event reports in the FDA FAERS database where RUXOLITINIB was used for Essential thrombocythaemia.
Most Reported Side Effects for RUXOLITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 12,492 | 18.3% | 1,527 | 1,769 |
| Death | 6,561 | 9.6% | 6,541 | 687 |
| Fatigue | 5,663 | 8.3% | 280 | 1,124 |
| Anaemia | 3,593 | 5.3% | 539 | 1,438 |
| Haemoglobin decreased | 3,297 | 4.8% | 456 | 1,306 |
| Platelet count decreased | 3,028 | 4.4% | 540 | 1,198 |
| Diarrhoea | 2,531 | 3.7% | 193 | 827 |
| Asthenia | 2,529 | 3.7% | 305 | 949 |
| Dizziness | 2,398 | 3.5% | 102 | 587 |
| Pneumonia | 2,343 | 3.4% | 643 | 1,726 |
| Headache | 2,271 | 3.3% | 97 | 541 |
| Product availability issue | 2,142 | 3.1% | 20 | 188 |
| Product dose omission issue | 2,130 | 3.1% | 41 | 281 |
| Dyspnoea | 2,042 | 3.0% | 258 | 886 |
| Splenomegaly | 1,995 | 2.9% | 292 | 686 |
Other Indications for RUXOLITINIB
Myelofibrosis (21,650)
Polycythaemia vera (12,352)
Myeloproliferative neoplasm (2,982)
Product used for unknown indication (2,869)
Graft versus host disease (2,291)
Primary myelofibrosis (2,234)
Chronic graft versus host disease (1,679)
Acute lymphocytic leukaemia (1,105)
Vitiligo (1,053)
Myelodysplastic syndrome (886)
Other Drugs Used for Essential thrombocythaemia
ANAGRELIDE (797)
HYDROXYUREA (629)
PEGINTERFERON ALFA-2A (259)
ROPEGINTERFERON ALFA-2B-NJFT (123)
ASPIRIN (77)
PACRITINIB (66)
LENALIDOMIDE (41)
FEDRATINIB (28)
XAGRID (27)
ASPIRIN DL-LYSINE (22)