SABRIL: 772 Adverse Event Reports & Safety Profile
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772
Total FAERS Reports
53 (6.9%)
Deaths Reported
180
Hospitalizations
772
As Primary/Secondary Suspect
6
Life-Threatening
1
Disabilities
First Report: 2010 · Latest Report: 20140618
What Are the Most Common SABRIL Side Effects?
#1 Most Reported
Drug dose omission
168 reports (21.8%)
#2 Most Reported
Convulsion
130 reports (16.8%)
#3 Most Reported
Drug ineffective
68 reports (8.8%)
All SABRIL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Drug dose omission | 168 | 21.8% | 1 | 11 |
| Convulsion | 130 | 16.8% | 5 | 54 |
| Drug ineffective | 68 | 8.8% | 0 | 3 |
| Death | 35 | 4.5% | 35 | 6 |
| Pneumonia | 31 | 4.0% | 6 | 28 |
| Incorrect dose administered | 27 | 3.5% | 0 | 2 |
| Vomiting | 26 | 3.4% | 1 | 8 |
| Somnolence | 25 | 3.2% | 0 | 3 |
| Wrong technique in drug usage process | 24 | 3.1% | 0 | 0 |
| Malaise | 19 | 2.5% | 1 | 10 |
| Pyrexia | 19 | 2.5% | 0 | 12 |
| Retinal toxicity | 18 | 2.3% | 0 | 0 |
| Drug withdrawal convulsions | 16 | 2.1% | 0 | 3 |
| Infantile spasms | 15 | 1.9% | 0 | 4 |
| Irritability | 13 | 1.7% | 0 | 4 |
| Abnormal behaviour | 12 | 1.6% | 0 | 0 |
| Respiratory distress | 12 | 1.6% | 3 | 12 |
| Visual impairment | 12 | 1.6% | 0 | 1 |
| Agitation | 11 | 1.4% | 1 | 1 |
| Fatigue | 11 | 1.4% | 0 | 2 |
Who Reports SABRIL Side Effects? Age & Gender Data
Average age: 11.0 years. Most reports from: US. View detailed demographics →
Is SABRIL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2010 | 2 | 0 | 0 |
| 2011 | 4 | 3 | 2 |
| 2012 | 8 | 2 | 3 |
| 2013 | 106 | 8 | 40 |
| 2014 | 258 | 23 | 92 |
What Is SABRIL Used For?
| Indication | Reports |
|---|---|
| Infantile spasms | 389 |
| Complex partial seizures | 144 |
| Epilepsy | 110 |
| Product used for unknown indication | 103 |
| Convulsion | 26 |
| Tuberous sclerosis | 26 |
| Temporal lobe epilepsy | 21 |
| Generalised tonic-clonic seizure | 14 |
| Grand mal convulsion | 10 |
| Generalised non-convulsive epilepsy | 7 |
SABRIL vs Alternatives: Which Is Safer?
SABRIL vs SACCHAROMYCES CEREVISIAE
SABRIL vs SACITUZUMAB GOVITECAN
SABRIL vs SACITUZUMAB GOVITECAN-HZIY
SABRIL vs SACROSIDASE
SABRIL vs SACUBITRIL
SABRIL vs SACUBITRIL\VALSARTAN
SABRIL vs SAFINAMIDE
SABRIL vs SAIZEN
SABRIL vs SALICYLATE
SABRIL vs SALICYLIC ACID
Official FDA Label for SABRIL
Official prescribing information from the FDA-approved drug label.