SELUMETINIB for Neurofibroma: Side Effects & Safety Data
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There are 192 adverse event reports in the FDA FAERS database where SELUMETINIB was used for Neurofibroma.
Most Reported Side Effects for SELUMETINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Blood creatine phosphokinase increased | 105 | 9.0% | 1 | 7 |
| Rash | 89 | 7.6% | 0 | 13 |
| Off label use | 78 | 6.7% | 4 | 6 |
| Paronychia | 73 | 6.2% | 1 | 8 |
| Dermatitis acneiform | 61 | 5.2% | 1 | 5 |
| Diarrhoea | 59 | 5.0% | 1 | 13 |
| Fatigue | 54 | 4.6% | 1 | 9 |
| Acne | 52 | 4.4% | 0 | 5 |
| Nausea | 49 | 4.2% | 0 | 15 |
| Death | 47 | 4.0% | 47 | 0 |
| Alopecia | 45 | 3.8% | 0 | 9 |
| Vomiting | 40 | 3.4% | 1 | 11 |
| Abdominal pain | 35 | 3.0% | 0 | 5 |
| Headache | 33 | 2.8% | 1 | 9 |
| Pruritus | 31 | 2.7% | 0 | 2 |
Other Indications for SELUMETINIB
Neurofibromatosis (499)
Brain neoplasm malignant (37)
Nervous system neoplasm benign (18)
Glioma (17)
Neoplasm malignant (15)
Neoplasm (14)
Non-small cell lung cancer (14)
Optic glioma (8)
Brain neoplasm (6)
Acute lymphocytic leukaemia (5)
Other Drugs Used for Neurofibroma
TRAMETINIB (60)
TRAMETINIB DIMETHYL SULFOXIDE (22)
BINIMETINIB (10)
IMATINIB (7)
DABRAFENIB (6)
MIRDAMETINIB (5)