Does SEVELAMER Cause Calciphylaxis? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Calciphylaxis have been filed in association with SEVELAMER (SEVELAMER CARBONATE). This represents 0.5% of all adverse event reports for SEVELAMER.
26
Reports of Calciphylaxis with SEVELAMER
0.5%
of all SEVELAMER reports
3
Deaths
12
Hospitalizations
How Dangerous Is Calciphylaxis From SEVELAMER?
Of the 26 reports, 3 (11.5%) resulted in death, 12 (46.2%) required hospitalization, and 4 (15.4%) were considered life-threatening.
Is Calciphylaxis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SEVELAMER. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does SEVELAMER Cause?
Constipation (2,041)
Pruritus (772)
Diarrhoea (665)
Nausea (484)
Vomiting (300)
Flatulence (217)
Abdominal pain (193)
Death (170)
Crystal deposit intestine (168)
Dyspepsia (141)
What Other Drugs Cause Calciphylaxis?
WARFARIN (639)
CALCIUM (141)
CINACALCET (141)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (135)
PREDNISONE (129)
CALCITRIOL (72)
PARICALCITOL (47)
PREDNISOLONE (47)
ERGOCALCIFEROL (42)
SODIUM THIOSULFATE (40)
Which SEVELAMER Alternatives Have Lower Calciphylaxis Risk?
SEVELAMER vs SEVOFLURANE
SEVELAMER vs SIBUTRAMINE
SEVELAMER vs SILDENAFIL
SEVELAMER vs SILODOSIN
SEVELAMER vs SILTUXIMAB