SILVER: 70 Adverse Event Reports & Safety Profile
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Active Ingredient: SILVER NITRATE · Route: ORAL · Manufacturer: Energique, Inc. · HUMAN OTC DRUG · FDA Label: Available
First Report: 1988 · Latest Report: 20230501
What Are the Most Common SILVER Side Effects?
All SILVER Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 29 | 41.4% | 7 | 11 |
| Drug hypersensitivity | 14 | 20.0% | 0 | 0 |
| Drug intolerance | 8 | 11.4% | 0 | 0 |
| Osteonecrosis of jaw | 8 | 11.4% | 0 | 1 |
| Headache | 7 | 10.0% | 0 | 1 |
| Wrong technique in product usage process | 6 | 8.6% | 0 | 0 |
| Nausea | 5 | 7.1% | 0 | 2 |
| Staphylococcal infection | 5 | 7.1% | 3 | 5 |
Who Reports SILVER Side Effects? Age & Gender Data
Gender: 58.0% female, 42.0% male. Average age: 52.5 years. Most reports from: US. View detailed demographics →
Is SILVER Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2002 | 1 | 1 | 0 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 0 |
| 2011 | 5 | 0 | 0 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 0 |
| 2015 | 2 | 1 | 0 |
| 2016 | 1 | 0 | 1 |
| 2017 | 4 | 1 | 1 |
| 2018 | 2 | 0 | 0 |
| 2019 | 4 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 0 |
What Is SILVER Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 21 |
| Wound treatment | 5 |
Official FDA Label for SILVER
Official prescribing information from the FDA-approved drug label.
Drug Description
DESCRIPTION Silver nitrate solution is a 0.5% solution of silver nitrate in a water medium. It is a topical anti-infective.
FDA Approved Uses (Indications)
Indications for Use For the relief of these symptoms due to minor wounds and burns, bruises, ulcerations, sunburn, razor burn, scrapes, rashes, blisters, bug bites, and skin eruptions from acne, eczema, or minor infection:
- burning
- stinging
- itching
- redness
- stiffness
- minor pain
- minor inflammation
Dosage & Administration
Dosage & Administration Prior to use, the applicator stick may be bent or shaped to allow easier access to the target area. The medicated end of the applicator should be moistened in clean water and applied to the affected tissue. One applicator is normally sufficient for each application. The strength of the action is controlled by the amount of water used to moisten the tip. The applicator action can be stopped by washing the area with a saline solution (0.9% sodium chloride).
Contraindications
Contraindications & Antidotes Caustic applicators must not be used for genital warts. Continued application to mucous membranes and open wounds leads to argyria, a bluish-black discoloration of the skin due to depositions of granules of silver compounds in the connective tissues. This condition persists indefinitely or disappears very slowly. Poisoning by oral ingestion is unlikely with the quantities involved, but treatment for poisoning is the immediate ingestion of large amounts of salt water followed by an emetic. Then administer a dose of Epsom Salts followed with milk. Immediately call a physician.
Warnings
Warnings Sore Throat Warning : Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a physician promptly.
- Do not use for more than 7 consecutive days. When using this product do not exceed recommended dosage. Stop use and ask a physician if : Sore throat symptoms do not improve in 7 days. Irritation, pain or redness persists or worsens.Swelling, rash or fever develops. If pregnant or breast-feeding : Ask a physician before use. Keep out of reach of children. Do not use if seal is broken.
Precautions
Precautions: Keep out of eyes. Should any sign of irritation or sensitivity occur consult your healthcare professional and discontinue use.
Active Ingredient
Active ingredient** (in each pellet) Argentum nitricum 30C HPUS (0.44 mg) (contains less than 10 -12 mg silver) The letters “HPUS” indicate that the component in this product is officially monographed in the Homeopathic Pharmacopoeia of the United States.
Inactive Ingredients
Inactive Ingredients Emu Oil, Isoamyl Laurate, Lactobacillus Ferment, Melaleuca Alternifolia (Tea Tree)
Leaf
Oil, Silica Dimethyl Silylate, Lysine HCl, Allantoin, Tocophyeryl Acetate, Squalane, Olive Oil, Water, Ceramine NP, Glyceryl Behenate, Hydrogenated Castor Oil, Citric Acid, Neopentyl Glycol Diheptanoate, Ethylhexyl Olivate, Vegetable Oil, Hydrogenated Vegetable Oil, Euphorbia Cerifera (Candella) Wax, Silver Citrate