SIMPONI for Crohn's disease: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where SIMPONI was used for Crohn's disease.
Most Reported Side Effects for SIMPONI
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Pneumonia | 50 | 7.1% | 3 | 28 |
| Drug ineffective | 36 | 5.1% | 0 | 5 |
| Device malfunction | 29 | 4.1% | 0 | 8 |
| Drug dose omission | 26 | 3.7% | 0 | 9 |
| Pain | 24 | 3.4% | 1 | 10 |
| Diarrhoea | 21 | 3.0% | 0 | 5 |
| Rheumatoid arthritis | 20 | 2.8% | 2 | 3 |
| Vomiting | 20 | 2.8% | 0 | 5 |
| Fall | 18 | 2.6% | 0 | 11 |
| Malaise | 18 | 2.6% | 0 | 6 |
| Off label use | 18 | 2.6% | 0 | 9 |
| Abdominal pain | 17 | 2.4% | 0 | 3 |
| Arthralgia | 16 | 2.3% | 1 | 4 |
| Dyspnoea | 16 | 2.3% | 0 | 8 |
| Nausea | 16 | 2.3% | 0 | 4 |
Other Indications for SIMPONI
Rheumatoid arthritis (365)
Product used for unknown indication (126)
Ankylosing spondylitis (77)
Psoriatic arthropathy (75)
Colitis ulcerative (26)
Spondylitis (7)
Psoriasis (5)
Other Drugs Used for Crohn's disease
ADALIMUMAB (99,540)
INFLIXIMAB (40,796)
VEDOLIZUMAB (28,718)
USTEKINUMAB (22,537)
RISANKIZUMAB-RZAA (12,561)
INFLIXIMAB-DYYB (10,657)
HUMIRA (10,174)
CERTOLIZUMAB PEGOL (8,758)
UPADACITINIB (4,390)
MESALAMINE (2,930)