Does SIROLIMUS Cause Chronic graft versus host disease? 167 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 167 reports of Chronic graft versus host disease have been filed in association with SIROLIMUS (sirolimus). This represents 1.5% of all adverse event reports for SIROLIMUS.
167
Reports of Chronic graft versus host disease with SIROLIMUS
1.5%
of all SIROLIMUS reports
34
Deaths
36
Hospitalizations
How Dangerous Is Chronic graft versus host disease From SIROLIMUS?
Of the 167 reports, 34 (20.4%) resulted in death, 36 (21.6%) required hospitalization, and 5 (3.0%) were considered life-threatening.
Is Chronic graft versus host disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 167 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Chronic graft versus host disease?
CYCLOSPORINE (1,012)
MYCOPHENOLATE MOFETIL (848)
METHOTREXATE (708)
TACROLIMUS (659)
CYCLOPHOSPHAMIDE (531)
FLUDARABINE (420)
RUXOLITINIB (321)
BUSULFAN (309)
PREDNISONE (251)
RITUXIMAB (244)
Which SIROLIMUS Alternatives Have Lower Chronic graft versus host disease Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE