Does SIROLIMUS Cause Endocarditis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Endocarditis have been filed in association with SIROLIMUS (sirolimus). This represents 0.2% of all adverse event reports for SIROLIMUS.
18
Reports of Endocarditis with SIROLIMUS
0.2%
of all SIROLIMUS reports
3
Deaths
13
Hospitalizations
How Dangerous Is Endocarditis From SIROLIMUS?
Of the 18 reports, 3 (16.7%) resulted in death, 13 (72.2%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which SIROLIMUS Alternatives Have Lower Endocarditis Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE