Does SIROLIMUS Cause Leukopenia? 109 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 109 reports of Leukopenia have been filed in association with SIROLIMUS (sirolimus). This represents 1.0% of all adverse event reports for SIROLIMUS.
109
Reports of Leukopenia with SIROLIMUS
1.0%
of all SIROLIMUS reports
20
Deaths
46
Hospitalizations
How Dangerous Is Leukopenia From SIROLIMUS?
Of the 109 reports, 20 (18.3%) resulted in death, 46 (42.2%) required hospitalization, and 6 (5.5%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
Yes, Leukopenia is listed as a known adverse reaction in the official FDA drug label for SIROLIMUS.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which SIROLIMUS Alternatives Have Lower Leukopenia Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE