SOLIRIS for Thrombotic microangiopathy: Side Effects & Safety Data
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There are 10 adverse event reports in the FDA FAERS database where SOLIRIS was used for Thrombotic microangiopathy.
Most Reported Side Effects for SOLIRIS
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 341 | 14.2% | 14 | 95 |
| Haemoglobin decreased | 254 | 10.6% | 12 | 122 |
| Transfusion | 183 | 7.6% | 8 | 67 |
| Abdominal pain | 141 | 5.9% | 8 | 69 |
| Unevaluable event | 140 | 5.8% | 17 | 129 |
| Dyspnoea | 129 | 5.4% | 10 | 57 |
| Headache | 126 | 5.3% | 3 | 49 |
| Aplastic anaemia | 120 | 5.0% | 4 | 27 |
| Death | 118 | 4.9% | 118 | 38 |
| Platelet count decreased | 106 | 4.4% | 12 | 60 |
| Haemolysis | 103 | 4.3% | 2 | 53 |
| Pyrexia | 103 | 4.3% | 11 | 78 |
| Haemoglobinuria | 100 | 4.2% | 5 | 34 |
| Off label use | 96 | 4.0% | 26 | 22 |
| Vomiting | 95 | 4.0% | 8 | 54 |
Other Indications for SOLIRIS
Paroxysmal nocturnal haemoglobinuria (1,478)
Haemolytic uraemic syndrome (811)
Off label use (102)
Product used for unknown indication (30)
Neuromyelitis optica (17)
Transplant rejection (8)
Glomerulonephritis membranoproliferative (5)
Other Drugs Used for Thrombotic microangiopathy
ECULIZUMAB (1,312)
CAPLACIZUMAB-YHDP (854)
RITUXIMAB (99)
RAVULIZUMAB-CWVZ (62)
METHYLPREDNISOLONE (56)
DEFIBROTIDE (34)
PREDNISOLONE (32)
PREDNISONE (30)
MYCOPHENOLATE MOFETIL (23)
CYCLOPHOSPHAMIDE (21)