Does SPIRONOLACTONE Cause Acidosis? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Acidosis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.3% of all adverse event reports for SPIRONOLACTONE.
55
Reports of Acidosis with SPIRONOLACTONE
0.3%
of all SPIRONOLACTONE reports
3
Deaths
27
Hospitalizations
How Dangerous Is Acidosis From SPIRONOLACTONE?
Of the 55 reports, 3 (5.5%) resulted in death, 27 (49.1%) required hospitalization, and 24 (43.6%) were considered life-threatening.
Is Acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Acidosis?
METFORMIN (427)
ACETAMINOPHEN (313)
EMPAGLIFLOZIN (179)
IBUPROFEN (162)
AMLODIPINE (133)
TRAMADOL (116)
TACROLIMUS (114)
MORPHINE (100)
QUETIAPINE (99)
PREDNISONE (94)
Which SPIRONOLACTONE Alternatives Have Lower Acidosis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE