Does SPIRONOLACTONE Cause Endocarditis? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Endocarditis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.1% of all adverse event reports for SPIRONOLACTONE.
13
Reports of Endocarditis with SPIRONOLACTONE
0.1%
of all SPIRONOLACTONE reports
10
Deaths
7
Hospitalizations
How Dangerous Is Endocarditis From SPIRONOLACTONE?
Of the 13 reports, 10 (76.9%) resulted in death, 7 (53.8%) required hospitalization, and 2 (15.4%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which SPIRONOLACTONE Alternatives Have Lower Endocarditis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE