SUGAMMADEX for Neuromuscular blockade: Side Effects & Safety Data
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There are 49 adverse event reports in the FDA FAERS database where SUGAMMADEX was used for Neuromuscular blockade.
Most Reported Side Effects for SUGAMMADEX
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Anaphylactic reaction | 338 | 14.8% | 12 | 140 |
| Bradycardia | 293 | 12.9% | 27 | 76 |
| Cardiac arrest | 198 | 8.7% | 30 | 71 |
| Bronchospasm | 182 | 8.0% | 7 | 52 |
| Anaphylactic shock | 176 | 7.7% | 6 | 69 |
| Hypotension | 155 | 6.8% | 10 | 50 |
| Recurrence of neuromuscular blockade | 113 | 5.0% | 5 | 29 |
| Drug ineffective | 108 | 4.7% | 1 | 36 |
| Oxygen saturation decreased | 91 | 4.0% | 2 | 38 |
| Off label use | 71 | 3.1% | 1 | 10 |
| Hypoxia | 59 | 2.6% | 3 | 27 |
| Blood pressure decreased | 55 | 2.4% | 7 | 19 |
| Maternal exposure during pregnancy | 53 | 2.3% | 0 | 6 |
| Dyspnoea | 52 | 2.3% | 2 | 20 |
| Tachycardia | 49 | 2.2% | 2 | 22 |
Other Indications for SUGAMMADEX
Neuromuscular blockade reversal (1,191)
Product used for unknown indication (128)
Anaesthesia reversal (86)
Anaesthesia (46)
Surgery (28)
General anaesthesia (25)
Adverse drug reaction (14)
Obstructive airways disorder (13)
Muscle relaxant therapy (12)
Reversal of sedation (12)
Other Drugs Used for Neuromuscular blockade
ROCURONIUM (204)
SUCCINYLCHOLINE (58)
CISATRACURIUM (45)
VECURONIUM (33)
ATRACURIUM (12)
LIDOCAINE (6)
ROPIVACAINE (5)