Does SUGAMMADEX Cause Hypercapnia? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Hypercapnia have been filed in association with SUGAMMADEX (BRIDION). This represents 0.4% of all adverse event reports for SUGAMMADEX.
9
Reports of Hypercapnia with SUGAMMADEX
0.4%
of all SUGAMMADEX reports
2
Deaths
1
Hospitalizations
How Dangerous Is Hypercapnia From SUGAMMADEX?
Of the 9 reports, 2 (22.2%) resulted in death, 1 (11.1%) required hospitalization, and 3 (33.3%) were considered life-threatening.
Is Hypercapnia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SUGAMMADEX. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does SUGAMMADEX Cause?
Anaphylactic reaction (338)
Bradycardia (293)
Cardiac arrest (198)
Bronchospasm (182)
Anaphylactic shock (176)
Hypotension (155)
Recurrence of neuromuscular blockade (113)
Drug ineffective (108)
Oxygen saturation decreased (91)
Off label use (71)
What Other Drugs Cause Hypercapnia?
ALBUTEROL (105)
MORPHINE (85)
PREDNISONE (69)
QUETIAPINE (67)
PREDNISOLONE (66)
MEPOLIZUMAB (62)
PREGABALIN (60)
METHYLPREDNISOLONE (56)
HYDROCORTISONE (55)
MACITENTAN (55)
Which SUGAMMADEX Alternatives Have Lower Hypercapnia Risk?
SUGAMMADEX vs SULBACTAM
SUGAMMADEX vs SULFACETAMIDE
SUGAMMADEX vs SULFADIAZINE
SUGAMMADEX vs SULFADIAZINE\TRIMETHOPRIM
SUGAMMADEX vs SULFAMETHOXAZOLE