TAFAMIDIS MEGLUMINE Drug Interactions: What You Need to Know
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Drug Interactions (FDA Label)
7. DRUG INTERACTIONS
7.1 BCRP Substrates Tafamidis inhibits breast cancer resistant protein (BCRP) in humans <span class="opacity-50 text-xs">[see Clinical Pharmacology (12.3) ]</span> . Coadministration of tafamidis and drugs that are BCRP substrates may increase the exposure of substrates of this transporter (e.g., methotrexate, rosuvastatin, imatinib) and the risk of the substrate-related toxicities. Monitor for signs of BCRP substrate-related toxicities and modify dosage of the substrate if appropriate.
Contraindications
4.
Contraindications
None. None. ( 4 )