TAMOXIFEN for Pik3ca-activated mutation: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where TAMOXIFEN was used for Pik3ca-activated mutation.
Most Reported Side Effects for TAMOXIFEN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Malignant neoplasm progression | 1,499 | 16.5% | 89 | 104 |
| Metastases to bone | 894 | 9.8% | 46 | 53 |
| Fatigue | 729 | 8.0% | 67 | 123 |
| Nausea | 611 | 6.7% | 68 | 222 |
| Metastases to liver | 595 | 6.5% | 44 | 42 |
| Breast cancer | 584 | 6.4% | 23 | 61 |
| Disease progression | 571 | 6.3% | 127 | 74 |
| Breast cancer metastatic | 515 | 5.7% | 26 | 47 |
| Diarrhoea | 512 | 5.6% | 78 | 185 |
| Arthralgia | 497 | 5.5% | 7 | 50 |
| Drug ineffective | 493 | 5.4% | 65 | 84 |
| Pain | 430 | 4.7% | 55 | 105 |
| Off label use | 388 | 4.3% | 59 | 95 |
| Headache | 374 | 4.1% | 51 | 95 |
| Neoplasm progression | 374 | 4.1% | 26 | 52 |
Other Indications for TAMOXIFEN
Breast cancer (2,931)
Product used for unknown indication (1,734)
Breast cancer metastatic (1,054)
Breast cancer female (403)
Invasive ductal breast carcinoma (347)
Her2 positive breast cancer (246)
Hormone receptor positive breast cancer (110)
Hormone therapy (92)
Neoplasm malignant (79)
Her-2 positive breast cancer (74)
Other Drugs Used for Pik3ca-activated mutation
ALPELISIB (150)
FULVESTRANT (36)
CAPIVASERTIB (6)
EVEROLIMUS (6)
RIBOCICLIB (6)
CYCLOPHOSPHAMIDE (5)
EPIRUBICIN (5)
EXEMESTANE (5)
PALBOCICLIB (5)