Does TENECTEPLASE Cause Aphasia? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Aphasia have been filed in association with TENECTEPLASE (TNKase). This represents 1.4% of all adverse event reports for TENECTEPLASE.
18
Reports of Aphasia with TENECTEPLASE
1.4%
of all TENECTEPLASE reports
3
Deaths
14
Hospitalizations
How Dangerous Is Aphasia From TENECTEPLASE?
Of the 18 reports, 3 (16.7%) resulted in death, 14 (77.8%) required hospitalization, and 5 (27.8%) were considered life-threatening.
Is Aphasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TENECTEPLASE. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does TENECTEPLASE Cause?
Off label use (430)
No adverse event (313)
Cerebral haemorrhage (132)
Angioedema (112)
Haemorrhage intracranial (74)
Haemorrhage (71)
Drug ineffective (68)
Death (60)
Haemorrhagic transformation stroke (49)
Cerebrovascular accident (45)
What Other Drugs Cause Aphasia?
METHOTREXATE (509)
ASPIRIN (468)
ADALIMUMAB (461)
DIMETHYL (438)
NATALIZUMAB (433)
METFORMIN (393)
AMLODIPINE (385)
ATORVASTATIN (356)
CARBIDOPA\LEVODOPA (356)
INTERFERON BETA-1A (343)
Which TENECTEPLASE Alternatives Have Lower Aphasia Risk?
TENECTEPLASE vs TENELIGLIPTIN
TENECTEPLASE vs TENIPOSIDE
TENECTEPLASE vs TENOFOVIR
TENECTEPLASE vs TENOFOVIR ALAFENAMIDE
TENECTEPLASE vs TENOFOVIR DISOPROXIL