Does TENECTEPLASE Cause Epistaxis? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Epistaxis have been filed in association with TENECTEPLASE (TNKase). This represents 1.2% of all adverse event reports for TENECTEPLASE.
16
Reports of Epistaxis with TENECTEPLASE
1.2%
of all TENECTEPLASE reports
1
Deaths
13
Hospitalizations
How Dangerous Is Epistaxis From TENECTEPLASE?
Of the 16 reports, 1 (6.3%) resulted in death, 13 (81.3%) required hospitalization, and 6 (37.5%) were considered life-threatening.
Is Epistaxis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TENECTEPLASE. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does TENECTEPLASE Cause?
Off label use (430)
No adverse event (313)
Cerebral haemorrhage (132)
Angioedema (112)
Haemorrhage intracranial (74)
Haemorrhage (71)
Drug ineffective (68)
Death (60)
Haemorrhagic transformation stroke (49)
Cerebrovascular accident (45)
What Other Drugs Cause Epistaxis?
RIVAROXABAN (5,629)
ASPIRIN (3,214)
APIXABAN (2,831)
FLUTICASONE (1,745)
TREPROSTINIL (1,726)
CLOPIDOGREL BISULFATE (1,560)
BEVACIZUMAB (1,542)
WARFARIN (1,498)
PALBOCICLIB (1,280)
ADALIMUMAB (1,243)
Which TENECTEPLASE Alternatives Have Lower Epistaxis Risk?
TENECTEPLASE vs TENELIGLIPTIN
TENECTEPLASE vs TENIPOSIDE
TENECTEPLASE vs TENOFOVIR
TENECTEPLASE vs TENOFOVIR ALAFENAMIDE
TENECTEPLASE vs TENOFOVIR DISOPROXIL