TENIPOSIDE for Retinoblastoma: Side Effects & Safety Data
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There are 69 adverse event reports in the FDA FAERS database where TENIPOSIDE was used for Retinoblastoma.
Most Reported Side Effects for TENIPOSIDE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Ototoxicity | 71 | 22.4% | 0 | 0 |
| Off label use | 61 | 19.2% | 10 | 4 |
| Product use in unapproved indication | 53 | 16.7% | 5 | 2 |
| Leukopenia | 25 | 7.9% | 3 | 2 |
| Bronchopulmonary aspergillosis | 21 | 6.6% | 20 | 0 |
| Anaemia | 20 | 6.3% | 2 | 1 |
| Histiocytosis haematophagic | 18 | 5.7% | 12 | 11 |
| Left ventricular dysfunction | 16 | 5.1% | 0 | 1 |
| Pancytopenia | 16 | 5.1% | 8 | 10 |
| Alopecia | 13 | 4.1% | 0 | 1 |
| Pneumocystis jirovecii pneumonia | 13 | 4.1% | 0 | 5 |
| Cardiotoxicity | 12 | 3.8% | 2 | 2 |
| Deafness | 12 | 3.8% | 0 | 0 |
| Neutropenia | 12 | 3.8% | 6 | 1 |
| Multiple organ dysfunction syndrome | 11 | 3.5% | 11 | 7 |
Other Indications for TENIPOSIDE
Acute lymphocytic leukaemia (58)
Burkitt's lymphoma (39)
Neuroblastoma (35)
Central nervous system lymphoma (19)
Diffuse large b-cell lymphoma (15)
Malignant lymphoid neoplasm (10)
Bone marrow conditioning regimen (9)
Non-hodgkin's lymphoma (9)
Rhabdomyosarcoma (6)
Burkitt's leukaemia (5)
Other Drugs Used for Retinoblastoma
MELPHALAN (715)
CARBOPLATIN (667)
VINCRISTINE (414)
ETOPOSIDE (316)
TOPOTECAN (302)
CYCLOPHOSPHAMIDE (131)
TOPOTECAN\TOPOTECAN (86)
DOXORUBICIN (43)
CISPLATIN (37)
THIOTEPA (24)