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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

THIOGUANINE ANHYDROUS: 1,168 Adverse Event Reports & Safety Profile

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1,168
Total FAERS Reports
175 (15.0%)
Deaths Reported
599
Hospitalizations
1,168
As Primary/Secondary Suspect
77
Life-Threatening
12
Disabilities

First Report: 1995 · Latest Report: 20250610

What Are the Most Common THIOGUANINE ANHYDROUS Side Effects?

#1 Most Reported
Febrile neutropenia
191 reports (16.4%)
#2 Most Reported
Off label use
98 reports (8.4%)
#3 Most Reported
Venoocclusive liver disease
85 reports (7.3%)

All THIOGUANINE ANHYDROUS Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Febrile neutropenia 191 16.4% 26 147
Off label use 98 8.4% 11 35
Venoocclusive liver disease 85 7.3% 6 26
Pancytopenia 74 6.3% 17 63
Pyrexia 72 6.2% 9 66
Drug ineffective 69 5.9% 11 40
Thrombocytopenia 63 5.4% 10 45
Anaemia 62 5.3% 9 36
Neutropenia 54 4.6% 4 43
Abdominal pain 53 4.5% 2 21
Pancreatitis 53 4.5% 0 26
Febrile bone marrow aplasia 48 4.1% 0 48
Vomiting 43 3.7% 3 40
Therapeutic product effect decreased 42 3.6% 0 18
Diarrhoea 41 3.5% 2 20
Leukopenia 41 3.5% 8 21
Venoocclusive disease 40 3.4% 22 17
Drug interaction 39 3.3% 0 7
Fatigue 38 3.3% 0 18
Multiple organ dysfunction syndrome 37 3.2% 32 9

Who Reports THIOGUANINE ANHYDROUS Side Effects? Age & Gender Data

Gender: 44.8% female, 55.2% male. Average age: 16.7 years. Most reports from: US. View detailed demographics →

Is THIOGUANINE ANHYDROUS Getting Safer? Reports by Year

YearReportsDeathsHosp.
2000 7 0 0
2010 3 0 0
2012 6 0 0
2013 11 1 8
2014 41 2 27
2015 14 1 6
2016 35 5 22
2017 189 5 138
2018 112 4 87
2019 41 2 36
2020 21 1 17
2021 45 4 35
2022 71 5 61
2023 15 1 9
2024 2 0 1
2025 19 1 15

View full timeline →

What Is THIOGUANINE ANHYDROUS Used For?

IndicationReports
Acute lymphocytic leukaemia 460
Crohn's disease 103
Product used for unknown indication 101
B precursor type acute leukaemia 51
Acute myeloid leukaemia 49
Precursor t-lymphoblastic lymphoma/leukaemia 34
Inflammatory bowel disease 30
T-cell type acute leukaemia 24
Colitis ulcerative 21
Acute lymphocytic leukaemia recurrent 12

THIOGUANINE ANHYDROUS vs Alternatives: Which Is Safer?

THIOGUANINE ANHYDROUS vs THIOPENTAL THIOGUANINE ANHYDROUS vs THIORIDAZINE THIOGUANINE ANHYDROUS vs THIOTEPA THIOGUANINE ANHYDROUS vs THIOTHIXENE THIOGUANINE ANHYDROUS vs THROMBIN THIOGUANINE ANHYDROUS vs THROMBIN HUMAN THIOGUANINE ANHYDROUS vs THYMOCYTE IMMUNE GLOBULIN NOS THIOGUANINE ANHYDROUS vs THYMOGLOBULINE THIOGUANINE ANHYDROUS vs THYMOL THIOGUANINE ANHYDROUS vs THYROID, PORCINE

Official FDA Label for THIOGUANINE ANHYDROUS

Official prescribing information from the FDA-approved drug label.