THIOGUANINE for Leukaemia: Side Effects & Safety Data
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There are 9 adverse event reports in the FDA FAERS database where THIOGUANINE was used for Leukaemia.
Most Reported Side Effects for THIOGUANINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 470 | 31.7% | 30 | 296 |
| Haematotoxicity | 174 | 11.8% | 30 | 7 |
| Off label use | 94 | 6.4% | 18 | 21 |
| Pyrexia | 80 | 5.4% | 4 | 70 |
| Sepsis | 76 | 5.1% | 21 | 43 |
| Febrile bone marrow aplasia | 73 | 4.9% | 0 | 72 |
| Neutropenia | 69 | 4.7% | 12 | 46 |
| Thrombocytopenia | 64 | 4.3% | 18 | 46 |
| Pancytopenia | 61 | 4.1% | 18 | 35 |
| Death | 49 | 3.3% | 49 | 3 |
| Vomiting | 45 | 3.0% | 2 | 38 |
| Toxicity to various agents | 43 | 2.9% | 30 | 22 |
| Mucosal inflammation | 42 | 2.8% | 4 | 24 |
| Product use in unapproved indication | 40 | 2.7% | 14 | 13 |
| Osteonecrosis | 38 | 2.6% | 1 | 10 |
Other Indications for THIOGUANINE
Acute lymphocytic leukaemia (638)
Precursor t-lymphoblastic lymphoma/leukaemia (119)
Acute myeloid leukaemia (88)
B precursor type acute leukaemia (78)
Non-hodgkin's lymphoma (68)
Product used for unknown indication (64)
B-cell type acute leukaemia (37)
Chemotherapy (36)
T-cell type acute leukaemia (36)
Precursor b-lymphoblastic lymphoma (31)
Other Drugs Used for Leukaemia
DASATINIB (654)
VENETOCLAX (307)
CYTARABINE (288)
METHOTREXATE (282)
IMATINIB (281)
RUXOLITINIB (230)
NILOTINIB (203)
BOSUTINIB (191)
VINCRISTINE (172)
CYCLOPHOSPHAMIDE (153)