THIOPENTAL for Induction of anaesthesia: Side Effects & Safety Data
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There are 163 adverse event reports in the FDA FAERS database where THIOPENTAL was used for Induction of anaesthesia.
Most Reported Side Effects for THIOPENTAL
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 266 | 25.4% | 57 | 168 |
| Off label use | 150 | 14.3% | 52 | 93 |
| Status epilepticus | 93 | 8.9% | 44 | 54 |
| Hypotension | 82 | 7.8% | 16 | 35 |
| Maternal exposure during pregnancy | 74 | 7.1% | 17 | 26 |
| Foetal exposure during pregnancy | 70 | 6.7% | 28 | 10 |
| Exposure during pregnancy | 64 | 6.1% | 7 | 26 |
| Product use in unapproved indication | 63 | 6.0% | 24 | 37 |
| Diabetes insipidus | 55 | 5.3% | 29 | 18 |
| Drug hypersensitivity | 45 | 4.3% | 0 | 13 |
| Loss of consciousness | 44 | 4.2% | 15 | 28 |
| Seizure | 44 | 4.2% | 18 | 29 |
| Multiple-drug resistance | 43 | 4.1% | 12 | 23 |
| Intensive care unit acquired weakness | 41 | 3.9% | 14 | 41 |
| Foetal death | 40 | 3.8% | 14 | 17 |
Other Indications for THIOPENTAL
Status epilepticus (223)
Product used for unknown indication (114)
Anaesthesia (105)
Seizure (88)
Endotracheal intubation (68)
General anaesthesia (56)
Epilepsy (37)
Foetal exposure during pregnancy (29)
Sedation (29)
New onset refractory status epilepticus (25)
Other Drugs Used for Induction of anaesthesia
PROPOFOL (2,072)
ROCURONIUM (955)
FENTANYL (904)
SUFENTANIL (580)
SEVOFLURANE (454)
LIDOCAINE (366)
KETAMINE (345)
REMIFENTANIL (331)
SUCCINYLCHOLINE (322)
MIDAZOLAM (295)