Does THIOTEPA Cause Myocarditis? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Myocarditis have been filed in association with THIOTEPA (Thiotepa). This represents 0.3% of all adverse event reports for THIOTEPA.
23
Reports of Myocarditis with THIOTEPA
0.3%
of all THIOTEPA reports
14
Deaths
2
Hospitalizations
How Dangerous Is Myocarditis From THIOTEPA?
Of the 23 reports, 14 (60.9%) resulted in death, 2 (8.7%) required hospitalization, and 20 (87.0%) were considered life-threatening.
Is Myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOTEPA. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Myocarditis?
CLOZAPINE (1,702)
PEMBROLIZUMAB (1,060)
NIVOLUMAB (959)
IPILIMUMAB (475)
OLANZAPINE (425)
ATEZOLIZUMAB (372)
CARBOPLATIN (325)
QUETIAPINE (315)
MESALAMINE (272)
BEVACIZUMAB (230)
Which THIOTEPA Alternatives Have Lower Myocarditis Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE