Does TOCILIZUMAB Cause Hypogammaglobulinaemia? 106 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 106 reports of Hypogammaglobulinaemia have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.1% of all adverse event reports for TOCILIZUMAB.
106
Reports of Hypogammaglobulinaemia with TOCILIZUMAB
0.1%
of all TOCILIZUMAB reports
17
Deaths
44
Hospitalizations
How Dangerous Is Hypogammaglobulinaemia From TOCILIZUMAB?
Of the 106 reports, 17 (16.0%) resulted in death, 44 (41.5%) required hospitalization, and 9 (8.5%) were considered life-threatening.
Is Hypogammaglobulinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 106 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Hypogammaglobulinaemia?
RITUXIMAB (1,762)
CYCLOPHOSPHAMIDE (780)
PREDNISONE (501)
MYCOPHENOLATE MOFETIL (416)
DEXAMETHASONE (400)
TISAGENLECLEUCEL (374)
PREDNISOLONE (367)
VINCRISTINE (355)
DOXORUBICIN (348)
METHOTREXATE (328)
Which TOCILIZUMAB Alternatives Have Lower Hypogammaglobulinaemia Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE