Does TOFACITINIB Cause Fluid retention? 454 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 454 reports of Fluid retention have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.3% of all adverse event reports for TOFACITINIB.
454
Reports of Fluid retention with TOFACITINIB
0.3%
of all TOFACITINIB reports
164
Deaths
227
Hospitalizations
How Dangerous Is Fluid retention From TOFACITINIB?
Of the 454 reports, 164 (36.1%) resulted in death, 227 (50.0%) required hospitalization, and 136 (30.0%) were considered life-threatening.
Is Fluid retention Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 454 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Fluid retention?
AMBRISENTAN (3,927)
TREPROSTINIL (3,804)
MACITENTAN (2,861)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (2,233)
SACUBITRIL\VALSARTAN (2,187)
ADALIMUMAB (1,193)
SELEXIPAG (1,044)
FUROSEMIDE (1,020)
LENALIDOMIDE (1,007)
EPOPROSTENOL (929)
Which TOFACITINIB Alternatives Have Lower Fluid retention Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN