Does TOFACITINIB Cause Hepatic cirrhosis? 620 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 620 reports of Hepatic cirrhosis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.4% of all adverse event reports for TOFACITINIB.
620
Reports of Hepatic cirrhosis with TOFACITINIB
0.4%
of all TOFACITINIB reports
337
Deaths
304
Hospitalizations
How Dangerous Is Hepatic cirrhosis From TOFACITINIB?
Of the 620 reports, 337 (54.4%) resulted in death, 304 (49.0%) required hospitalization, and 265 (42.7%) were considered life-threatening.
Is Hepatic cirrhosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 620 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Hepatic cirrhosis?
ADALIMUMAB (1,760)
METHOTREXATE (1,650)
ETANERCEPT (931)
TOCILIZUMAB (903)
RITUXIMAB (863)
INFLIXIMAB (831)
ABATACEPT (824)
HYDROXYCHLOROQUINE (807)
LEFLUNOMIDE (780)
SULFASALAZINE (760)
Which TOFACITINIB Alternatives Have Lower Hepatic cirrhosis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN