Does TOFACITINIB Cause Rheumatic fever? 2,373 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,373 reports of Rheumatic fever have been filed in association with TOFACITINIB (XELJANZ XR). This represents 1.5% of all adverse event reports for TOFACITINIB.
2,373
Reports of Rheumatic fever with TOFACITINIB
1.5%
of all TOFACITINIB reports
1,354
Deaths
1,411
Hospitalizations
How Dangerous Is Rheumatic fever From TOFACITINIB?
Of the 2,373 reports, 1,354 (57.1%) resulted in death, 1,411 (59.5%) required hospitalization, and 1,510 (63.6%) were considered life-threatening.
Is Rheumatic fever Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 2,373 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Rheumatic fever?
ABATACEPT (2,726)
TOCILIZUMAB (2,725)
METHOTREXATE (2,700)
RITUXIMAB (2,618)
LEFLUNOMIDE (2,609)
DICLOFENAC (2,583)
ADALIMUMAB (2,572)
ALENDRONATE (2,565)
PREDNISONE (2,552)
DESOXIMETASONE (2,535)
Which TOFACITINIB Alternatives Have Lower Rheumatic fever Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN