Does TOPIRAMATE Cause Hyperchloraemia? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Hyperchloraemia have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.
17
Reports of Hyperchloraemia with TOPIRAMATE
0.1%
of all TOPIRAMATE reports
2
Deaths
8
Hospitalizations
How Dangerous Is Hyperchloraemia From TOPIRAMATE?
Of the 17 reports, 2 (11.8%) resulted in death, 8 (47.1%) required hospitalization, and 10 (58.8%) were considered life-threatening.
Is Hyperchloraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Hyperchloraemia?
SODIUM (214)
LORAZEPAM (32)
DIAZEPAM (22)
VENLAFAXINE (17)
CLOMIPRAMINE (15)
ASPIRIN (14)
BROMAZEPAM (14)
DULOXETINE (14)
ACETAMINOPHEN (12)
IBUPROFEN (12)
Which TOPIRAMATE Alternatives Have Lower Hyperchloraemia Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB