Does TOPIRAMATE Cause Hyperkalaemia? 15 Reports in FDA Database

Q: Does TOPIRAMATE cause Hyperkalaemia?

15 reports of Hyperkalaemia have been filed with the FDA for TOPIRAMATE, representing 0.1% of all TOPIRAMATE adverse event reports.

Q: How dangerous is Hyperkalaemia from TOPIRAMATE?

Of 15 reports, 2 (13.3%) resulted in death and 13 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hyperkalaemia have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.

Reports of Hyperkalaemia with TOPIRAMATE

0.1%

of all TOPIRAMATE reports

Deaths

Hospitalizations

How Dangerous Is Hyperkalaemia From TOPIRAMATE?

Of the 15 reports, 2 (13.3%) resulted in death, 13 (86.7%) required hospitalization, and 8 (53.3%) were considered life-threatening.

Is Hyperkalaemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 15 reports have been filed with the FAERS database.

What Other Side Effects Does TOPIRAMATE Cause?

Drug ineffective (5,553) Off label use (4,248) Product use in unapproved indication (2,173) Headache (1,997) Drug intolerance (1,820) Migraine (1,796) Nausea (1,691) Seizure (1,535) Paraesthesia (1,506) Dizziness (1,466)

What Other Drugs Cause Hyperkalaemia?

METFORMIN (2,565) SPIRONOLACTONE (2,518) FUROSEMIDE (2,035) RAMIPRIL (1,383) SACUBITRIL\VALSARTAN (1,192) SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036) LISINOPRIL (948) POTASSIUM (944) BISOPROLOL (850) TACROLIMUS (713)

Which TOPIRAMATE Alternatives Have Lower Hyperkalaemia Risk?

TOPIRAMATE vs TOPOTECAN TOPIRAMATE vs TOPOTECAN\TOPOTECAN TOPIRAMATE vs TOPROL TOPIRAMATE vs TOREMIFENE TOPIRAMATE vs TORIPALIMAB

TOPIRAMATE Full Profile All Hyperkalaemia Reports All Drugs Causing Hyperkalaemia TOPIRAMATE Demographics