Does TOPIRAMATE Cause Mania? 106 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 106 reports of Mania have been filed in association with TOPIRAMATE (Topiramate). This represents 0.4% of all adverse event reports for TOPIRAMATE.
106
Reports of Mania with TOPIRAMATE
0.4%
of all TOPIRAMATE reports
0
Deaths
39
Hospitalizations
How Dangerous Is Mania From TOPIRAMATE?
Of the 106 reports, 39 (36.8%) required hospitalization, and 24 (22.6%) were considered life-threatening.
Is Mania Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 106 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Mania?
ARIPIPRAZOLE (924)
QUETIAPINE (574)
LURASIDONE (544)
OLANZAPINE (520)
SERTRALINE (438)
RISPERIDONE (353)
LAMOTRIGINE (331)
LITHIUM (323)
VENLAFAXINE (319)
DULOXETINE (296)
Which TOPIRAMATE Alternatives Have Lower Mania Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB