Does TOPIRAMATE Cause Status epilepticus? 315 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 315 reports of Status epilepticus have been filed in association with TOPIRAMATE (Topiramate). This represents 1.1% of all adverse event reports for TOPIRAMATE.
315
Reports of Status epilepticus with TOPIRAMATE
1.1%
of all TOPIRAMATE reports
74
Deaths
161
Hospitalizations
How Dangerous Is Status epilepticus From TOPIRAMATE?
Of the 315 reports, 74 (23.5%) resulted in death, 161 (51.1%) required hospitalization, and 51 (16.2%) were considered life-threatening.
Is Status epilepticus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 315 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Status epilepticus?
LEVETIRACETAM (1,883)
LACOSAMIDE (874)
VALPROIC ACID (587)
PHENYTOIN (544)
BUPROPION (490)
LAMOTRIGINE (438)
MIDAZOLAM (369)
CLOBAZAM (366)
PHENOBARBITAL (317)
PROPOFOL (288)
Which TOPIRAMATE Alternatives Have Lower Status epilepticus Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB