Does TRASTUZUMAB Cause Onycholysis? 109 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 109 reports of Onycholysis have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.2% of all adverse event reports for TRASTUZUMAB.
109
Reports of Onycholysis with TRASTUZUMAB
0.2%
of all TRASTUZUMAB reports
1
Deaths
9
Hospitalizations
How Dangerous Is Onycholysis From TRASTUZUMAB?
Of the 109 reports, 1 (0.9%) resulted in death, 9 (8.3%) required hospitalization, and 8 (7.3%) were considered life-threatening.
Is Onycholysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 109 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Onycholysis?
PACLITAXEL (173)
DOCETAXEL (130)
SECUKINUMAB (82)
ADALIMUMAB (77)
CAPECITABINE (73)
METHOTREXATE (67)
PERTUZUMAB (55)
ERDAFITINIB (44)
CARBOPLATIN (42)
ETANERCEPT (41)
Which TRASTUZUMAB Alternatives Have Lower Onycholysis Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE